Pub. Date : 2009 May
PMID : 19228205
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cytochrome P450 2B6 516G-->T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population. | Nevirapine | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 2 | OBJECTIVES: The aim of the study was to characterize the impact of the cytochrome P450 2B6 (CYP2B6), CYP3A4, CYP3A5 and ATP-binding cassette sub-family B member 1 (ABCB1) polymorphisms on nevirapine plasma concentrations. | Nevirapine | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 3 | OBJECTIVES: The aim of the study was to characterize the impact of the cytochrome P450 2B6 (CYP2B6), CYP3A4, CYP3A5 and ATP-binding cassette sub-family B member 1 (ABCB1) polymorphisms on nevirapine plasma concentrations. | Nevirapine | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 4 | The association between CYP2B6 516G-->T and higher plasma nevirapine exposure was maintained at both bid and qd dosing. | Nevirapine | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |