Title : EGF receptor signaling is involved in expression of osmoprotective TonEBP target gene aldose reductase under hypertonic conditions.

Pub. Date : 2009 May

PMID : 19225051






1 Functional Relationships(s)
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1 Conversely, the broad-spectrum MMP inhibitor GM6001 or the EGFR inhibitor AG1478 diminished phosphorylation of EGFR, p38, and ERK1/2, the induction of AR mRNA and protein, and AR promoter reporter activity in response to hypertonicity. RTKI cpd mitogen-activated protein kinase 1 Canis lupus familiaris