Pub. Date : 2009 Mar 1
PMID : 19223512
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The objective of our study was to quantitatively assess N-glycans originating from serum glycoproteins as alternative markers for the detection of HCC. | n-glycans | HCC | Homo sapiens |
| 2 | RESULTS: The abundance of 57 N-glycans was significantly altered in HCC patients compared with controls. | n-glycans | HCC | Homo sapiens |
| 3 | A combination of three selected N-glycans was sufficient to classify HCC with 90% sensitivity and 89% specificity in an independent validation set of patients with chronic liver disease. | n-glycans | HCC | Homo sapiens |
| 4 | The three N-glycans remained associated with HCC after adjustment for chronic viral infection and other known covariates, whereas the other glycans increased significantly at earlier stages of the progression of chronic viral infection to HCC. | n-glycans | HCC | Homo sapiens |
| 5 | CONCLUSION: A set of three identified N-glycans is sufficient for the detection of HCC with 90% prediction accuracy in a population with high rates of hepatitis C viral infection. | n-glycans | HCC | Homo sapiens |