Title : Protein kinase Cbeta is an effective target for chemoprevention of colon cancer.

Pub. Date : 2009 Feb 15

PMID : 19221092






1 Functional Relationships(s)
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1 We find that enzastaurin potently reduces azoxymethane-induced colon tumor initiation and progression by inhibiting PKCbetaII-mediated tumor cell proliferation and beta-catenin accumulation. Azoxymethane catenin (cadherin associated protein), beta 1 Mus musculus