Title : Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma.

Pub. Date : 2009 Aug

PMID : 19220580






2 Functional Relationships(s)
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1 Treatment of 10-0505 tumours with sorafenib plus rapamycin resulted in growth inhibition, inhibition of vascular endothelial growth factor receptor-2 phosphorylation, increased apoptosis and completely blocked sorafenib-induced phosphorylation of mTOR targets and cyclin B1 expression. Sorafenib cyclin B1 Homo sapiens
2 Treatment of 10-0505 tumours with sorafenib plus rapamycin resulted in growth inhibition, inhibition of vascular endothelial growth factor receptor-2 phosphorylation, increased apoptosis and completely blocked sorafenib-induced phosphorylation of mTOR targets and cyclin B1 expression. Sorafenib cyclin B1 Homo sapiens