Title : Bad targets the permeability transition pore independent of Bax or Bak to switch between Ca2+-dependent cell survival and death.

Pub. Date : 2009 Feb 13

PMID : 19217411






1 Functional Relationships(s)
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1 Thus, phospho-regulatory mechanisms converge on Bad to switch between the survival and apoptotic functions of mitochondrial calcium signaling by activating a mechanism whereby a BH3-only protein bypasses Bax/Bak and engages the PTP. Calcium BCL2 associated X, apoptosis regulator Homo sapiens