Title : Cyclooxygenase-2-derived prostaglandin E2 is involved in vascular endothelial growth factor production in interleukin-1alpha-stimulated human periodontal ligament cells.

Pub. Date : 2009 Jun

PMID : 19210337






4 Functional Relationships(s)
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Protein Name
Organism
1 Cyclooxygenase-2-derived prostaglandin E2 is involved in vascular endothelial growth factor production in interleukin-1alpha-stimulated human periodontal ligament cells. Dinoprostone vascular endothelial growth factor A Homo sapiens
2 Exogenous prostaglandin E(2), butaprost (an EP2 receptor agonist) and dibutyryl cAMP abolished the inhibitory effect of indomethacin on interleukin-1alpha-induced vascular endothelial growth factor production. Dinoprostone vascular endothelial growth factor A Homo sapiens
3 CONCLUSION: We suggest that interleukin-1alpha induced vascular endothelial growth factor production via cyclooxygenase-2-derived prostaglandin E(2) in human periodontal ligament cells. Dinoprostone vascular endothelial growth factor A Homo sapiens
4 The interleukin-1alpha/prostaglandin E(2) pathway might regulate vascular endothelial growth factor production in periodontal lesions. Dinoprostone vascular endothelial growth factor A Homo sapiens