Title : Synthesis, SAR, and biological evaluation of alpha-sulfonylphosphonic acids as selective matrix metalloproteinase inhibitors.

Pub. Date : 2009 Mar

PMID : 19204958






1 Functional Relationships(s)
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1 The mode of binding of the new phosphonates in the active site of MMP-2 was studied, and variations in inhibition was explained by means of molecular modeling. Organophosphonates matrix metallopeptidase 2 Homo sapiens