Title : Effect of some bis Mannich bases and corresponding piperidinols on DNA topoisomerase I.

Pub. Date : 2008

PMID : 19202742






1 Functional Relationships(s)
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1 Some acetophenone (CAS 98-86-2) derived bis Mannich bases, bis-(3-aryl-3-oxo-propyl)-methylamine hydrochlorides (B1-B5) and representative piperidinols, 4-aryl-3-arylcarbonyl-1-methyl-4-piperidinol hydrochlorides (C1, C2 and C5), which are the structural isomers of B1, B2 and B5, were synthesized and their effects on DNA topoisomerase I were tested. acetophenone immunoglobulin kappa variable 7-3 (pseudogene) Homo sapiens