Title : Discovery of imidazo[1,2-b]thiazole derivatives as novel SIRT1 activators.

Pub. Date : 2009 Mar 12

PMID : 19199480






1 Functional Relationships(s)
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1 A series of imidazo[1,2-b]thiazole derivatives is shown to activate the NAD(+)-dependent deacetylase SIRT1, a potential new therapeutic target to treat various metabolic disorders. NAD sirtuin 1 Mus musculus