Title : L-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice.

Pub. Date : 2009 Feb

PMID : 19187092






1 Functional Relationships(s)
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1 In 6-hydroxydopamine-lesioned Drd2-EGFP mice, L-DOPA increased the phosphorylation of ERK, mitogen- and stress-activated kinase 1 and histone H3, selectively in EGFP-negative MSNs. Levodopa H3 clustered histone 7 Mus musculus