Title : SARS coronavirus spike protein-induced innate immune response occurs via activation of the NF-kappaB pathway in human monocyte macrophages in vitro.

Pub. Date : 2009 Jun

PMID : 19185596






1 Functional Relationships(s)
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1 An NF-kappaB inhibitor, TPCK (N-Tosyl-L-Phenylalanine Chloromethyl Ketone) could suppress IL-8 production and secretion in response to S protein in PBMC and THP-1 cells and in HCoV-229E virus-infected PBMC. Tosylphenylalanyl Chloromethyl Ketone C-X-C motif chemokine ligand 8 Homo sapiens