Pub. Date : 2009 Jan
PMID : 19173110
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Long-term administration of salicylate enhances prestin expression in rat cochlea. | Salicylates | solute carrier family 26 member 5 | Rattus norvegicus |
| 2 | In this experiment, we assessed the effect of acute and chronic salicylate treatment on prestin expression. | Salicylates | solute carrier family 26 member 5 | Rattus norvegicus |
| 3 | Interestingly, after long-term salicylate injection (200 mg/kg, twice daily for 14 days), prestin gene and protein levels were up-regulated about twofold. | Salicylates | solute carrier family 26 member 5 | Rattus norvegicus |
| 4 | These data reveal that chronic salicylate administration markedly, but reversibly, increased prestin levels which may contribute to the enhanced DPOAE amplitudes we observed previously with similar salicylate treatment, which may be responsible for salicylate-induced tinnitus generation. | Salicylates | solute carrier family 26 member 5 | Rattus norvegicus |
| 5 | These data reveal that chronic salicylate administration markedly, but reversibly, increased prestin levels which may contribute to the enhanced DPOAE amplitudes we observed previously with similar salicylate treatment, which may be responsible for salicylate-induced tinnitus generation. | Salicylates | solute carrier family 26 member 5 | Rattus norvegicus |
| 6 | These data reveal that chronic salicylate administration markedly, but reversibly, increased prestin levels which may contribute to the enhanced DPOAE amplitudes we observed previously with similar salicylate treatment, which may be responsible for salicylate-induced tinnitus generation. | Salicylates | solute carrier family 26 member 5 | Rattus norvegicus |