Title : Response of bladder carcinoma cells to TRAIL and antisense oligonucleotide, Bcl-2 or clusterin treatments.

Pub. Date : 2009 Mar

PMID : 19157446






1 Functional Relationships(s)
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1 RESULTS: Although no direct correlation between TRAIL sensitivity and the relative expression levels of Bcl-2 and clusterin was found in the bladder transitional cell carcinoma cell lines examined, antisense oligonucleotide mediated the down-regulation of Bcl-2 and clusterin, increasing the sensitivity of the partially resistant cells to TRAIL. Oligonucleotides TNF superfamily member 10 Homo sapiens