Title : Modulation of sphingolipid metabolism by the phosphatidylinositol-4-phosphate phosphatase Sac1p through regulation of phosphatidylinositol in Saccharomyces cerevisiae.

Pub. Date : 2009 Mar 20

PMID : 19139096






1 Functional Relationships(s)
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1 Deletion of SAC1 decreased PtdIns dramatically in both steady-state and pulse labeling studies, suggesting that the observed effects on sphingolipids may result from modulation of the availability of PtdIns as a substrate for Aur1p. Sphingolipids inositol phosphorylceramide synthase Saccharomyces cerevisiae S288C