Title : F 15845 inhibits persistent sodium current in the heart and prevents angina in animal models.

Pub. Date : 2009 Jan

PMID : 19133985






1 Functional Relationships(s)
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1 CONCLUSIONS AND IMPLICATIONS: F 15845 is a selective, potent blocker of the persistent sodium current, generated by the human Na(v)1.5 channel isoforms, and prevents cardiac angina in animal models. Sodium immunoglobulin lambda variable 2-18 Homo sapiens