Pub. Date : 2008 Sep
PMID : 19119629
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [Effects of genistein on expression of TGF-beta1 and intracellular free Ca2+ concentration in fibroblasts derived from human hypertrophic scar]. | Genistein | transforming growth factor beta 1 | Homo sapiens |
| 2 | OBJECTIVE: To observe the effects of Genistein on TGF-beta1 expression and the intracellular free Ca2+ concentration in human hypertrophic scar fibroblasts, and to discuss the mechanism of the anti-fibrosis effect. | Genistein | transforming growth factor beta 1 | Homo sapiens |
| 3 | RESULTS: Genistein inhibited the expression of TGF-beta1 in hypertrophic scar fibroblasts on a concentration-dependent manner. | Genistein | transforming growth factor beta 1 | Homo sapiens |
| 4 | CONCLUSIONS: Genistein can reduce the expression of TGF-beta1 and block the accumulation of intracellular free calcium induced by growth factors. | Genistein | transforming growth factor beta 1 | Homo sapiens |