Title : Effects of memantine and galantamine given separately or in association, on memory and hippocampal neuronal loss after transient global cerebral ischemia in gerbils.

Pub. Date : 2009 Feb 13

PMID : 19103181






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In this study, the association of 10 mg/kg memantine with 10 mg/kg galantamine increased the number of living pyramidal neurons, reduced TUNEL, active caspase-3 and SOD-2 immunoreactivity, and preserved spatial memory after ischemia-reperfusion injury; however, the effects of the combination were not statistically different from those observed in animals treated with galantamine alone. Galantamine caspase 3 Homo sapiens