Pub. Date : 2009 Apr
PMID : 19092850
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Role of catalase in monocytic differentiation of U937 cells by TPA: hydrogen peroxide as a second messenger. | Tetradecanoylphorbol Acetate | catalase | Homo sapiens |
| 2 | TPA treatment decreased the expression level of catalase, which catalyzes the decomposition of hydrogen peroxide (H(2)O(2)) to H(2)O and O(2). | Tetradecanoylphorbol Acetate | catalase | Homo sapiens |
| 3 | Treatment of U937 cells with catalase inhibited the enhancement of ROS generation induced by TPA, and blocked the TPA-induced differentiation of U937 cells. | Tetradecanoylphorbol Acetate | catalase | Homo sapiens |
| 4 | Treatment of U937 cells with catalase inhibited the enhancement of ROS generation induced by TPA, and blocked the TPA-induced differentiation of U937 cells. | Tetradecanoylphorbol Acetate | catalase | Homo sapiens |
| 5 | However, HP100-1 cells, its variant cell line overexpressing catalase, were resistant to TPA-induced differentiation. | Tetradecanoylphorbol Acetate | catalase | Homo sapiens |
| 6 | Our results suggest that catalase inhibits monocytic differentiation by TPA; the decrease in catalase level and the accumulation of H(2)O(2) are significant events for monocyte/macrophage differentiation by TPA. | Tetradecanoylphorbol Acetate | catalase | Homo sapiens |
| 7 | Our results suggest that catalase inhibits monocytic differentiation by TPA; the decrease in catalase level and the accumulation of H(2)O(2) are significant events for monocyte/macrophage differentiation by TPA. | Tetradecanoylphorbol Acetate | catalase | Homo sapiens |
| 8 | Our results suggest that catalase inhibits monocytic differentiation by TPA; the decrease in catalase level and the accumulation of H(2)O(2) are significant events for monocyte/macrophage differentiation by TPA. | Tetradecanoylphorbol Acetate | catalase | Homo sapiens |