Title : Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control.

Pub. Date : 2009 Feb 13

PMID : 19060337






1 Functional Relationships(s)
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Protein Name
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1 In cells deficient in both Chk1 and p53, Cdc25A down-regulation upon camptothecin-induced DNA damage is completely abolished, leading to severe defects in cell cycle checkpoints and remarkable cell death in mitosis. Camptothecin tumor protein p53 Homo sapiens