Title : Effects of vaccinia virus uracil DNA glycosylase catalytic site and deoxyuridine triphosphatase deletion mutations individually and together on replication in active and quiescent cells and pathogenesis in mice.

Pub. Date : 2008 Dec 2

PMID : 19055736






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Deoxyuridine triphosphatase (dUTPase) hydrolyzes dUTP, generating dUMP for biosynthesis of thymidine nucleotides while decreasing the availability of dUTP for misincorporation; uracil DNA glycosylase (UNG) cleaves uracil N-glycosylic bonds in DNA initiating base excision repair. Uracil Deoxyuridine triphosphatase Drosophila melanogaster