Title : Coordinated control of connexin 26 and connexin 30 at the regulatory and functional level in the inner ear.

Pub. Date : 2008 Dec 2

PMID : 19047647






2 Functional Relationships(s)
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1 The coordinated regulation of Cx26 and Cx30 expression appears to occur as a result of signaling through PLC and the NF-kappaB pathway, because activation of IP(3)-mediated Ca(2+) responses by stimulation of P2Y receptors for 20 min with 20 nM ATP increased the levels of Cx26 transcripts in Cx30 KO cultures. Inositol 1,4,5-Trisphosphate gap junction protein beta 6 Homo sapiens
2 The coordinated regulation of Cx26 and Cx30 expression appears to occur as a result of signaling through PLC and the NF-kappaB pathway, because activation of IP(3)-mediated Ca(2+) responses by stimulation of P2Y receptors for 20 min with 20 nM ATP increased the levels of Cx26 transcripts in Cx30 KO cultures. Inositol 1,4,5-Trisphosphate gap junction protein beta 6 Homo sapiens