Title : Is autophagy rather than apoptosis the regression driver in imatinib-treated gastrointestinal stromal tumors?

Pub. Date : 2008 Dec

PMID : 19043528






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Sampling areas with different residual cellularity scores fromboth the imatinib-treated and untreated patients showed biochemical and immunohistochemical evidence of high levels of proautophagy beclin1/PI3KIII and low levels of antiautophagy beclin1/bcl2 complexes, together with the presence of LC3-II detected by Western blot analysis, thus supporting the presence of autophagy. Imatinib Mesylate peptidase inhibitor 3 Homo sapiens