Pub. Date : 2009 Apr
PMID : 19036857
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | However, transfection of astrocytes with dominant negative forms of the helicases implicated MDA-5, but not RIG-I, as the intracellular sensor of poly I:C. Complexed poly I:C-mediated MDA-5 stimulation transmitted "downstream" signals, resulting in activation of the transcription factors NF-kappaB and IRF-3. | Poly I | interferon induced with helicase C domain 1 | Mus musculus |
| 2 | However, transfection of astrocytes with dominant negative forms of the helicases implicated MDA-5, but not RIG-I, as the intracellular sensor of poly I:C. Complexed poly I:C-mediated MDA-5 stimulation transmitted "downstream" signals, resulting in activation of the transcription factors NF-kappaB and IRF-3. | Poly I | interferon induced with helicase C domain 1 | Mus musculus |