Title : Oncogenic HRAS mutations cause prolonged PI3K signaling in response to epidermal growth factor in fibroblasts of patients with Costello syndrome.

Pub. Date : 2009 Mar

PMID : 19035362






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 HRAS is one of the three classical RAS proteins and cycles between an active, GTP- and an inactive, GDP-bound conformation. Guanosine Triphosphate HRas proto-oncogene, GTPase Homo sapiens
2 The GTP-bound form of HRAS was significantly enriched in CS compared with normal fibroblasts. Guanosine Triphosphate HRas proto-oncogene, GTPase Homo sapiens