Title : HSP90 is required for TAK1 stability but not for its activation in the pro-inflammatory signaling pathway.

Pub. Date : 2008 Dec 10

PMID : 19026643






1 Functional Relationships(s)
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1 However, Hsp90 is not required for the activation of TAK1 as short exposure to the Hsp90 inhibitor, 17-(allylamino)-17-demethoxygeldanamycin (17-AAG) did not affect its activation by LPS or IL-1. tanespimycin N-methylpurine DNA glycosylase Homo sapiens