Title : Aldo-keto reductases from the AKR1B subfamily: retinoid specificity and control of cellular retinoic acid levels.

Pub. Date : 2009 Mar 16

PMID : 19014918






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 With all-trans-retinaldehyde, AKR1B10 shows a much higher k(cat) value than AKR1B1 (18 min(-1)vs. 0.37 min(-1)) and a catalytic efficiency comparable to that of the best retinaldehyde reductases. Retinaldehyde aldo-keto reductase family 1 member B10 Homo sapiens
2 Overall it is suggested that the rate-limiting step in the reaction mechanism with retinaldehyde differs between AKR1B1 and AKR1B10. Retinaldehyde aldo-keto reductase family 1 member B10 Homo sapiens