Title : Induction of cytoplasmic accumulation of p53: a mechanism for low levels of arsenic exposure to predispose cells for malignant transformation.

Pub. Date : 2008 Nov 15

PMID : 19010883






1 Functional Relationships(s)
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1 We report here that treatment of cells with sodium arsenite at the concentrations close to environmental exposure is associated with the up-regulation of Hdm2 and the accumulation of p53 in the cytoplasm. sodium arsenite tumor protein p53 Homo sapiens