Title : The effects of desvenlafaxine and paroxetine on the pharmacokinetics of the cytochrome P450 2D6 substrate desipramine in healthy adults.

Pub. Date : 2009 Feb

PMID : 19001559






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The effects of desvenlafaxine and paroxetine on the pharmacokinetics of the cytochrome P450 2D6 substrate desipramine in healthy adults. Desipramine cytochrome P450 family 2 subfamily D member 6 Homo sapiens
2 The CYP2D6 substrate desipramine (50 mg) was administered alone on day 1 and coadministered on day 6 of dosing with either desvenlafaxine or paroxetine. Desipramine cytochrome P450 family 2 subfamily D member 6 Homo sapiens