Title : Multiple glycines in TCR alpha-chains determine clonally diverse nature of human T cell memory to influenza A virus.

Pub. Date : 2008 Nov 15

PMID : 18981164






1 Functional Relationships(s)
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1 Repertoires of T cell memory are discussed in the context of clonal diversity, where poly-Gly/Ala runs in the CDR3 of alpha- and beta-chains might provide high levels of TCR flexibility during Ag recognition while gene-encoded CDR1 and CDR2 contribute to the fine specificity of the TCR-peptide MHC interaction. Alanine major histocompatibility complex, class I, C Homo sapiens