Title : Nicotinic acetylcholine receptor activation mediates nicotine-induced enhancement of experimental periodontitis.

Pub. Date : 2009 Feb

PMID : 18973546






2 Functional Relationships(s)
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1 RESULTS: Compared with saline/saline-treated control rats, saline/nicotine-treated rats developed significantly more periodontal bone loss, and LPS provoked a significantly smaller increase in circulating levels of the cytokines tumour necrosis factor alpha (TNF-alpha), transforming growth factor 1beta (TGF-1beta) and interleukin-10 (IL-10). Nicotine interleukin 10 Rattus norvegicus
2 RESULTS: Compared with saline/saline-treated control rats, saline/nicotine-treated rats developed significantly more periodontal bone loss, and LPS provoked a significantly smaller increase in circulating levels of the cytokines tumour necrosis factor alpha (TNF-alpha), transforming growth factor 1beta (TGF-1beta) and interleukin-10 (IL-10). Nicotine interleukin 10 Rattus norvegicus