Title : Inhibition of tumour necrosis factor and IL-17 production by leflunomide involves the JAK/STAT pathway.

Pub. Date : 2009 Oct

PMID : 18957484






1 Functional Relationships(s)
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1 RESULTS: Treatment of PBL with leflunomide, cyclosporin A and FK-506 inhibited the IL-15-induced expression of both CD54 and CD69 by PBL, as well as TNF production in co-cultures of activated PBL and THP-1 cells. Tacrolimus tumor necrosis factor Homo sapiens