Title : [The regulation of stat3 signal transduction pathway to G1 to S phase of laryngocarcinoma cell].

Pub. Date : 2008 Aug

PMID : 18950011






1 Functional Relationships(s)
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1 METHOD: Human laryngocarcinoma cell lines Hep-2 were transfected with Stat3 antisense oligonucleotide mediated by liposome, MTT assay was used to measure the proliferation, flow cytometry was applied to analyze the cell cycle, and the expressions of Stat3, phosphorylation specific Stat3 (tyrosine705), CyclinD1, Cyclin E, CDK2, CDK4, CDK6, p21 and p27 were detected by western blot. monooxyethylene trimethylolpropane tristearate signal transducer and activator of transcription 3 Homo sapiens