Title : Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells.

Pub. Date : 2008 Dec 15

PMID : 18929641

1 Functional Relationships(s)
Compound Name
Protein Name
1 Interleukin-1beta, flagellin, interferon-gamma, and tumor necrosis factor alpha (TNF-alpha) similarly induced Nox1 in a colon cancer cell line (T84), whereas only TNF-alpha fully induced NOXO1 and upregulated superoxide-producing activity by ninefold. Superoxides interleukin 1 beta Homo sapiens