Title : Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription.

Pub. Date : 2008 Dec 12

PMID : 18922798






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Phosphorylation of FE65 tyrosine 547 within the PTB2 domain has been shown to enhance FE65-APP-mediated transcription but not to influence binding to APP. Tyrosine amyloid beta precursor protein binding family B member 1 Homo sapiens
2 Phosphorylation of FE65 tyrosine 547 within the PTB2 domain has been shown to enhance FE65-APP-mediated transcription but not to influence binding to APP. Tyrosine amyloid beta precursor protein binding family B member 1 Homo sapiens
3 Thus, Dexras1 functions as a suppressor of FE65-APP-mediated transcription, and FE65 tyrosine 547 phosphorylation enhances FE65-APP-mediated transcription, at least in part, by modulating the interaction between FE65 and Dexras1. Tyrosine amyloid beta precursor protein binding family B member 1 Homo sapiens
4 Thus, Dexras1 functions as a suppressor of FE65-APP-mediated transcription, and FE65 tyrosine 547 phosphorylation enhances FE65-APP-mediated transcription, at least in part, by modulating the interaction between FE65 and Dexras1. Tyrosine amyloid beta precursor protein binding family B member 1 Homo sapiens
5 Thus, Dexras1 functions as a suppressor of FE65-APP-mediated transcription, and FE65 tyrosine 547 phosphorylation enhances FE65-APP-mediated transcription, at least in part, by modulating the interaction between FE65 and Dexras1. Tyrosine amyloid beta precursor protein binding family B member 1 Homo sapiens