Pub. Date : 2008 Apr
PMID : 18850198
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The present study was designed to investigate the effects of isoflavone genistein exposure at concentrations ranging from 0.01 to 50 muM on the LDL receptor and HMG-CoA reductase gene expression in the estrogen receptor positive DLD-1 human colon cancer cell line. | Genistein | 3-hydroxy-3-methylglutaryl-CoA reductase | Homo sapiens |
| 2 | Genistein induced an increase of LDL receptor gene expression and later decrease of HMG-CoA reductase mRNA expression in DLD-1 cells. | Genistein | 3-hydroxy-3-methylglutaryl-CoA reductase | Homo sapiens |
| 3 | These findings provide direct evidence on the role of genistein in regulating LDL receptor and HMG-CoA reductase gene expression in colon cancer. | Genistein | 3-hydroxy-3-methylglutaryl-CoA reductase | Homo sapiens |