Title : The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway.

Pub. Date : 2008 Oct 15

PMID : 18843116






1 Functional Relationships(s)
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1 We argue that these new findings indicate that SPAK and OSR1 are promising drug targets for the treatment of hypertension, because inhibiting these enzymes would reduce NCC and NKCC2 activity and thereby suppress renal salt re-absorption. Salts solute carrier family 12 member 3 Homo sapiens