Pub. Date : 2008 Dec
PMID : 18841476
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In addition, GSNO was found to induce accumulation of p53 in normal but not HIF-1alpha knockdown THP-1 cells, where expression of this protein was silenced by specific siRNA. | S-Nitrosoglutathione | tumor protein p53 | Homo sapiens |
2 | It has also been found that GSNO-mediated accumulation of p53 depends on activation of ASK1 since no GSNO-induced p53 stabilisation was observed in THP-1 cells transfected with dominant-negative form of this kinase. | S-Nitrosoglutathione | tumor protein p53 | Homo sapiens |