Pub. Date : 2009 Mar
PMID : 18837472
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Since the dysregulation of beta-catenin metabolism and its transcriptional activity in addition to a decreased intercellular communication has been causally linked to the development of colon cancer while a low Bcl-2 expression is associated with a worse prognosis in colon cancer, the reversal of these early changes may be important events in the prevention of colon cancer by orally administered sphingolipids, and may provide specific molecular biomarkers for sphingolipid efficacy in vivo. | Sphingolipids | B cell leukemia/lymphoma 2 | Mus musculus |
| 2 | Since the dysregulation of beta-catenin metabolism and its transcriptional activity in addition to a decreased intercellular communication has been causally linked to the development of colon cancer while a low Bcl-2 expression is associated with a worse prognosis in colon cancer, the reversal of these early changes may be important events in the prevention of colon cancer by orally administered sphingolipids, and may provide specific molecular biomarkers for sphingolipid efficacy in vivo. | Sphingolipids | B cell leukemia/lymphoma 2 | Mus musculus |