Title : Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone.

Pub. Date : 2008 Nov 28

PMID : 18829454






2 Functional Relationships(s)
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1 Functionally, CID755673 inhibited the known biological actions of PKD1 including phorbol ester-induced class IIa histone deacetylase 5 nuclear exclusion, vesicular stomatitis virus glycoprotein transport from the Golgi to the plasma membrane, and the ilimaquinone-induced Golgi fragmentation. CID755673 polycystin 1, transient receptor potential channel interacting Homo sapiens
2 In summary, our findings indicate that CID755673 is a potent and selective PKD1 inhibitor with valuable pharmacological and cell biological potential. CID755673 polycystin 1, transient receptor potential channel interacting Homo sapiens