Title : The impact of sodium chloride and volume depletion in the chronic kidney disease of congenital chloride diarrhea.

Pub. Date : 2008 Oct

PMID : 18827800






1 Functional Relationships(s)
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1 Congenital chloride diarrhea is due to mutations in the intestinal Cl(-)/HCO(3)(-) exchange (SLC26A3) which results in sodium chloride and fluid depletion leading to hypochloremic and hypokalemic metabolic alkalosis. Sodium Chloride solute carrier family 26 member 3 Homo sapiens