Pub. Date : 2009 Mar
PMID : 18823436
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Anti-gastric cancer effects of celecoxib, a selective COX-2 inhibitor, through inhibition of Akt signaling. | Celecoxib | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | CONCLUSION: The anti-cancer effects of celecoxib on gastric cancer cells might be partly mediated by downregulation of Akt, GSK3beta, FKHR, and upregulation of caspase-9, in the mitochondrial apoptotic pathway. | Celecoxib | AKT serine/threonine kinase 1 | Homo sapiens |