Title : Inhibitors of GlyT1 affect glycine transport via discrete binding sites.

Pub. Date : 2008 Dec

PMID : 18815213






1 Functional Relationships(s)
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1 Because glycine is a coagonist of the N-methyl-D-aspartate (NMDA) receptor (NMDAR), which has been implicated in schizophrenia, inhibition of GlyT1 is thought to provide an option for the treatment of schizophrenia. Glycine glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis