Title : WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis.

Pub. Date : 2008 Dec

PMID : 18806757






1 Functional Relationships(s)
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1 The knockdown of WWP1 by siRNA increases the endogenous DeltaNp63alpha level in the MCF10A and 184B5 immortalized breast epithelial cell lines and confers resistance to doxorubicin-induced apoptosis. deltanp63alpha WW domain containing E3 ubiquitin protein ligase 1 Homo sapiens