Title : Estrogen protects the heart from ischemia-reperfusion injury via COX-2-derived PGI2.

Pub. Date : 2008 Sep

PMID : 18806603






1 Functional Relationships(s)
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1 To determine the effects of COX-2 inhibition on infarct size after E2 treatment, New Zealand white rabbits were anesthetized and administered the COX-2 inhibitor nimesulide (5 mg/kg) or vehicle intravenously 30 minutes before an intravenous injection of E2. nimesulide cytochrome c oxidase subunit II Oryctolagus cuniculus