Title : K-ras cancer gene mutations in lung tumors from female Swiss (CD-1) mice exposed transplacentally to 3'-azido-3'-deoxythymidine.

Pub. Date : 2008 Dec

PMID : 18800350






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 K-ras Codon 12 G-->T transversions (TGT mutations) may be induced by oxidative DNA damage and 8-oxoguanine (8-oxoG), while K-ras Codon 12 G-->C transversions (CGT mutations) may be due to further oxidative lesions of guanine and 8-oxoG. Guanine UDP galactosyltransferase 8A Mus musculus