Pub. Date : 2008 Dec 1
PMID : 18793663
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DNA repair activity, measured as OGG1 base excision repair (BER) activity, increased by approximately 1.3 fold in the nuclear protein extracts (NE) and approximately 1.2 fold in the mitochondrial protein extracts (ME) of spleens from aniline-treated rats as compared to the controls. | aniline | 8-oxoguanine DNA glycosylase | Rattus norvegicus |
| 2 | Real-time PCR analysis for OGG1 mRNA expression in the spleen revealed a 2-fold increase in expression in aniline-treated rats than the controls. | aniline | 8-oxoguanine DNA glycosylase | Rattus norvegicus |
| 3 | Likewise, OGG1 protein expression in the NEs of spleens from aniline-treated rats was approximately 1.5 fold higher, whereas in the MEs it was approximately 1.3 fold higher than the controls. | aniline | 8-oxoguanine DNA glycosylase | Rattus norvegicus |
| 4 | Aniline treatment also led to stronger immunostaining for both 8-OHdG and OGG1 in the spleens, confined to the red pulp areas. | aniline | 8-oxoguanine DNA glycosylase | Rattus norvegicus |