Title : High-resolution mass spectrometry analysis of protein oxidations and resultant loss of function.

Pub. Date : 2008 Oct

PMID : 18793185






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Dose-response inactivation by 4HNE (4-hydroxynonenal) of hBAT (human bile acid CoA:amino acid N-acyltransferase) and CKBB (cytosolic brain isoform of creatine kinase) is associated with site-specific modifications. 4-hydroxy-2-nonenal bile acid-CoA:amino acid N-acyltransferase Homo sapiens
2 Dose-response inactivation by 4HNE (4-hydroxynonenal) of hBAT (human bile acid CoA:amino acid N-acyltransferase) and CKBB (cytosolic brain isoform of creatine kinase) is associated with site-specific modifications. 4-hydroxy-2-nonenal bile acid-CoA:amino acid N-acyltransferase Homo sapiens
3 Dose-response inactivation by 4HNE (4-hydroxynonenal) of hBAT (human bile acid CoA:amino acid N-acyltransferase) and CKBB (cytosolic brain isoform of creatine kinase) is associated with site-specific modifications. 4-hydroxy-2-nonenal bile acid-CoA:amino acid N-acyltransferase Homo sapiens
4 Dose-response inactivation by 4HNE (4-hydroxynonenal) of hBAT (human bile acid CoA:amino acid N-acyltransferase) and CKBB (cytosolic brain isoform of creatine kinase) is associated with site-specific modifications. 4-hydroxy-2-nonenal bile acid-CoA:amino acid N-acyltransferase Homo sapiens
5 At 4HNE concentrations in the physiological range, one member of the catalytic triad of hBAT (His362) was modified; for CKBB, although all four residues in the active site that were modifiable by 4HNE were ultimately modified, only one, Cys283, occurred at physiological concentrations of 4HNE. 4-hydroxy-2-nonenal bile acid-CoA:amino acid N-acyltransferase Homo sapiens