Pub. Date : 2008 Oct
PMID : 18793185
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Dose-response inactivation by 4HNE (4-hydroxynonenal) of hBAT (human bile acid CoA:amino acid N-acyltransferase) and CKBB (cytosolic brain isoform of creatine kinase) is associated with site-specific modifications. | 4-hydroxy-2-nonenal | bile acid-CoA:amino acid N-acyltransferase | Homo sapiens |
2 | Dose-response inactivation by 4HNE (4-hydroxynonenal) of hBAT (human bile acid CoA:amino acid N-acyltransferase) and CKBB (cytosolic brain isoform of creatine kinase) is associated with site-specific modifications. | 4-hydroxy-2-nonenal | bile acid-CoA:amino acid N-acyltransferase | Homo sapiens |
3 | Dose-response inactivation by 4HNE (4-hydroxynonenal) of hBAT (human bile acid CoA:amino acid N-acyltransferase) and CKBB (cytosolic brain isoform of creatine kinase) is associated with site-specific modifications. | 4-hydroxy-2-nonenal | bile acid-CoA:amino acid N-acyltransferase | Homo sapiens |
4 | Dose-response inactivation by 4HNE (4-hydroxynonenal) of hBAT (human bile acid CoA:amino acid N-acyltransferase) and CKBB (cytosolic brain isoform of creatine kinase) is associated with site-specific modifications. | 4-hydroxy-2-nonenal | bile acid-CoA:amino acid N-acyltransferase | Homo sapiens |
5 | At 4HNE concentrations in the physiological range, one member of the catalytic triad of hBAT (His362) was modified; for CKBB, although all four residues in the active site that were modifiable by 4HNE were ultimately modified, only one, Cys283, occurred at physiological concentrations of 4HNE. | 4-hydroxy-2-nonenal | bile acid-CoA:amino acid N-acyltransferase | Homo sapiens |