Title : Androgen-independent prostate cancer cells acquire the complete steroidogenic potential of synthesizing testosterone from cholesterol.

Pub. Date : 2008 Nov 25

PMID : 18782595






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1 In the present study, we have determined the potential of prostate cancer cells to synthesize androgens from cholesterol which may be involved in intracrine regulation of AR in advanced stages of the disease. Cholesterol androgen receptor Homo sapiens