Pub. Date : 2008 Oct 31
PMID : 18772138
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Regulation of interleukin-8 gene at a distinct site of its promoter by CCAAT enhancer-binding protein homologous protein in prostaglandin E2-treated human T cells. | Dinoprostone | C-X-C motif chemokine ligand 8 | Homo sapiens |
2 | We have previously shown that in human T lymphocytes the CHOP phosphorylation induced by prostaglandin E(2) (PGE(2))-increased interleukin-8 (IL-8) gene expression. | Dinoprostone | C-X-C motif chemokine ligand 8 | Homo sapiens |
3 | We have previously shown that in human T lymphocytes the CHOP phosphorylation induced by prostaglandin E(2) (PGE(2))-increased interleukin-8 (IL-8) gene expression. | Dinoprostone | C-X-C motif chemokine ligand 8 | Homo sapiens |
4 | The IL-8/AP-1 mutant promoter lacking the sequence immediately upstream the AP-1 site is PGE(2)-unresponsive. | Dinoprostone | C-X-C motif chemokine ligand 8 | Homo sapiens |
5 | Finally, chromatin immunoprecipitation data confirmed in vivo that PGE(2) induces CHOP binding to the IL-8 promoter. | Dinoprostone | C-X-C motif chemokine ligand 8 | Homo sapiens |